Peptides

[Stay safe always]

Anybody on peptides? Thinking of starting in RETA, wanna see if anybody has any experiences to share? 
 

[leckmich]

https://www.nytimes.com/2026/01/03/business/chinese-peptides-silicon-valley.html

 

"

The F.D.A. has warned that many peptides pose “serious safety risks” because of potential impurities and immune reactions. It has also barred pharmacies from compounding them, though enforcement is uneven.

Personal use is legal, though most doctors advise against it. “It’s unfounded and reckless,” said Dr. Eric Topol, director of the Scripps Research Translational Institute, a research center focused on individualized medicine."

 

 

https://www.nytimes.com/2026/03/31/health/peptide-ban-fda-rfk-jr.html

 

 

"

Dr. Raizman said he had seen some clinicians in the sports medicine field embrace the restricted peptides. One of the products closely resembles drugs that have serious side effects, including a painful, hourslong erection. Another peptide was approved in Eastern Europe but not in the United States. A third is referred to as the “Barbie drug” and is meant to enhance tanning, exposing patients to risk for a limited benefit.

 

Since 2012, when an outbreak of fungal meningitis caused by an injectable painkiller made by the New England Compounding Center killed at least 64 people and sickened hundreds of others, career agency officials have been particularly wary of small compounding pharmacies. But over the last few years, the pharmacies have experienced a surge in business through selling cheaper, copycat versions of weight loss drugs — a practice the F.D.A. has recently cracked down on."

Edited June 17 by leckmich

[MasterFitMalaySG4U]

Some locals used but act or pretend they don't use it...it is clearly can tell ..why need to gatekeep? Haha 

 

But still best seek your family or fav doctor to confirmed as our body varies from others. Especially different blood types, your past medical etc......

[juicyass]

On 6/17/2026 at 6:20 PM, Stay safe always said:

Anybody on peptides? Thinking of starting in RETA, wanna see if anybody has any experiences to share? 
 

 

what is your aim in using peptide? 

[Stay safe always]

Lose body fat with RETA

[abcwater]

1 hour ago, Stay safe always said:

Lose body fat with RETA

You can also lose body fat by consistent and disciplined diet. 

[bodybuildMLY]

2 hours ago, Stay safe always said:

Lose body fat with RETA

 

HSA and FDA aside, you need someone to guide you on using Retatrutide or GLP-1, because it will affect your gut health and you need to mitigate it by taking certain precautions. 

[juicyass]

2 hours ago, Stay safe always said:

Lose body fat with RETA

 

mannnn.. what you need is to start a simple nutrition plan for your fat loss goal. Get advice from chatgpt, it will help you a lot.

I have been using chatgpt to track my fitness progress and i already see great results from it. 

[Stay safe always]

So anybody on RETA here? 

[Damienzo]

I have a doctor friend who supplies Mounjaro (by Lily Pharmaceuticals) for weight loss and it is selling very well. According to him, Mounjaro is similar price levels to Ozempic and works significantly better. He has tried it himself too. 
Anyone who would like to consider and need a referral to him can DM me. 

Edited June 26 by Damienzo

[HendryTan]

https://cnalifestyle.channelnewsasia.com/wellness/glp1-drugs-ozempic-longevity-585541

______________________________________________________________________________
Are Ozempic and other weight loss drugs also longevity drugs? Here's what early research suggests

Experts are intrigued by the theory. Here’s what early research suggests.

12 Jul 2026 07:11AM

 

A theory that GLP-1 medications such as Ozempic or Zepbound might help people live longer has been bandied about by biohackers and ageing researchers for several years. Online pharmacies already market compounded versions of the drugs to purportedly extend health span. But so far, academic research into that hypothesis has been scant.

 

One of the first studies putting the idea to the test was published last month. It showed that, among people with HIV and lipohypertrophy (fatty deposits that develop under the skin), taking semaglutide (the drug in Ozempic) for eight months seemed to slow participants’ biological ageing, according to blood tests that measure age-related biomarkers. 

People with HIV experience accelerated ageing because of the infection, so they are a good population in which to conduct age-related research, said Michael Corley, an associate professor of medicine at UC San Diego’s Stein Institute for Research on Aging, who led the study.

 

The trial was preliminary, but it “provided us an opportunity to say, hey, is there any signal here that warrants all the hype?” Corley said.

That hype stems from several lines of evidence. First, there is ample research demonstrating that GLP-1s improve people’s metabolic health by helping to regulate insulin and blood sugar and causing weight loss. Several studies show that they also benefit cardiovascular, liver and kidney health.

Because the drugs offer protection for conditions like diabetes and cardiovascular disease, which are both among the leading causes of death, it could already be reasonable to call GLP-1s longevity drugs.

 

“GLP-1 agonists decrease the incidence of diseases that are related to ageingand are associated with decreasing lifespan,” said Dr Nicolas Musi, director of the Diabetes and Aging Center at Cedars-Sinai in Los Angeles. “One would assume that they’re also potentially going to increase lifespan and be beneficial for longevity,” he added.

Another reason experts think these drugs might increase longevity is because of how they affect cellular health. Metabolic health and ageing are intricately linked, so drugs that alter the mechanisms involved in metabolism may also affect how the body ages.

“Many of these pathways that are modulated by diabetes drugs are also central pathways that control ageing and longevity,” Musi said. (Other drugs that treat diabetes, like metformin and a category known as SGLT2 inhibitors, are similarly being studied for longevity, though the evidence so far has been mixed.)

GLP-1s appear to influence other fundamental cellular changes that occur with aging, most notably inflammation. “We know they have a significant anti-inflammatory effect, and we know inflammation is one of the things that accelerates aging,” said Dr Thomas Blackwell, a professor of general internal medicine at the University of Texas Medical Branch in Galveston.

All of this sounds promising, but researchers say there’s a huge caveat: Currently little to no data exists on whether the drugs will benefit people who are metabolically healthy.

There is not even data available about whether the medications extend lifespan in rodents. Dr Richard Miller, a professor of pathology at the University of Michigan, who runs a large programme there testing potential anti-ageing drugs in mice, said that’s mainly because of logistics. Currently available GLP-1s either don’t work in mice the same way they do in humans, or can be delivered only via injection, and giving mice weekly injections for years is not practical.

There are also concerns that GLP-1s negatively affect health in ways that are especially relevant for aging. Most notably, the drugs can cause some muscle loss, a major issue for older adults that is associated with an increased risk of frailty. Rapid weight loss can also lead to a decline in bone density and an increased risk of osteoporosis.

A few clinical trials that are testing GLP-1s on several biomarkers of ageing, such as inflammation levels and biological age clocks, as well as on functional abilities such as strength and walking speed, are finally getting underway. 

At least one of the studies still will not be conducted on healthy older adults, though, since the participants need to meet the criteria for receiving a prescription for the weight loss medications, said Blackwell, who is leading the trial. But he added that those criteria – for example, a body mass index of 27 or greater and a related health condition, like high blood pressure – reflect “a whole lot of Americans.”

For now, experts generally don’t recommend taking the medications off label for longevity. “In patients that are otherwise healthy, at this point, I think it’s premature, because there are no data justifying it from preclinical or clinical studies,” Musi said.

In Blackwell’s case, the message seemed to be: Do as I say, not as I do. He has been taking tirzepatide (the drug in Zepbound) for the past year with the goal of slowing ageing.

 

"Do I know that that’s the right thing? I do not,” he said. “Do I recommend that for patients? I do not.”

“This is my own personal decision,” he added.

By Dana G Smith © The New York Times Company